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High levels of potassium in your blood hyperkalemia ; kidney failure; a urinary tract infection; untreated or uncontrolled diabetes; addison s disease an adrenal gland disorder ; a large tissue injury such as a severe burn; a peptic ulcer in your stomach; if you are severely dehydrated; or if you are taking a potassium-sparing diuretic water pill such as amiloride midamor, moduretic , spironolactone aldactone, aldactazide , triamterene dyrenium, dyazide, maxzide .
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Alcohol diuretics such as hydrochlorothiazide found in many blood pressure medicines diuretics that don t wash out potassium, such as spironolactone aldactone and the diuretic component in dyazide, maxzide, moduretic, and others.
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— salicylates decreases the diuretic effect of aldactone due to blockade of canrenone excretion by the kidneys.
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aldactone may also be given with diuretics that act more proximally in the renal tubule or with other antihypertensive agents.